Dental Management in a Child Patient with Glucose-6-phosphate Dehydrogenase Deficiency : A Case Report
전지윤, 양선미, 최남기, 김선미,
소속 상세정보
전지윤 ( Jeon Ji-Yoon ) - Chonnam National University School of Dentistry Department of Pediatric Dentistry
양선미 ( Yang Sun-Mi ) - Chonnam National University School of Dentistry Department of Pediatric Dentistry
최남기 ( Choi Nam-Ki ) - Chonnam National University School of Dentistry Department of Pediatric Dentistry
김선미 ( Kim Seon-Mi ) - Chonnam National University School of Dentistry Department of Pediatric Dentistry
Abstract
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked recessive disorder and is the most common enzyme deficiency worldwide. Although this disease is rare in Korea, its prevalence may increase due to an increase of multicultural families. Patients with this deficiency are prone to hemolytic anemia provoked by specific drugs commonly used or prescribed in pediatric dentistry. It is necessary for pediatric dentists to have accurate knowledge of a patient's medical history and to consult with a pediatric hematologist to avoid oxidative stress that can lead to hemolysis. The most effective treatment is prevention of exposure to factors that may trigger anemia. Appropriate education regarding risk factors is essential for patients diagnosed with this disease. This case report aimed to discuss the drugs and dental management methods that should be cautious in children with G6PD deficiency.
키워드
Glucose-6-phosphate dehydrogenase deficiency; Hemolytic anemia; Oxidative stress; Pediatric dentistry
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